The shapes of letters and their fonts may play a part in dyslexia. It's not my area of expertise. This emerging research is interesting though.
The Science Daily article outlines the research done in Victoria University
"The next time you are reading a book, or even as you read this article, consider the words that you are seeing. How do you recognize these words? Substantial research has shown that while reading, we recognize words by their letters and not by the general shape of the word. However, it was largely unknown how we differentiate one letter from another. The full article is here